Sunday, May 25, 2014

The Recommended Dosage For Forskolin

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The recommended dosage should be based upon the level of forskolin. Future studies will undoubtedly produce more precise dosage recommendations of a Coleus forskohlii. The current recommendation for Coleus forskohlii extract, standardized to contain 185 forskolin, is 50 mg (9 mg of forskolin) two to three times daily. The animal studies on forskolin indicate an extremely low order of toxicity for forskolin. Based on the pharmacology of forskolin, it may be wise to restrict the use of C. forskohlii preparations in cases of low blood pressure and peptic ulcers. Furthermore, C. forskohlii preparations should be used with caution in patients on presription medications especially anti-asthmatics and anti-hypertensives due to its ability to possibly potentiate the drug's effect. Another holistic medicinal herb that is only recently being discovered in the Western world, forskolin has been used as a natural and holistic form of medicine in the East for centuries. The plant, Coleus Forskohlii, grows in the temperate regions of India, Myanmar and Thailand, and from it comes the organic compound forskolin. Forskolin is the active component of the Coleus herb and has been the focus of extensive research for its purported healing properties in a large number of diseases.

The key mechanism of action that Forskolin induces is increasing the amount of cyclic adenosine monophosphate (AMP) in the cells by stimulating the enzyme adenylate cyclase. Keep in mind that this Cyclic AMP act as important second messengers, so-called because they bind hormones to receptors and trigger certain biological processes. Technical talk aside, an increase of cyclic AMP in the body brings with it many positive effects and benefits. It aids in the treatment of several illnesses and prevents the onset of many more. Such is the marvel of forskolin, as the natives of the countries where it abounds have known long ago and the scientists are only just beginning to realize. You have to ensure that you know about this before you are going to take it. .